Chronic Kidney Disease

Chronic renal failure

Additionally called chronic kidney disease, describes the gradual loss of kidney function. Your kidneys filter wastes and excess fluids from your blood, that square measure then excreted in your urine. once chronic renal failure reaches an advanced stage, dangerous levels of fluid, electrolytes and wastes can accumulate in your body.

In the early stages of chronic kidney disease, you may have few signs or symptoms. Chronic renal failure might not become apparent until your kidney function is considerably impaired.

Treatment for chronic renal failure focuses on swiftness the progression of the kidney injury, typically by controlling the underlying cause. Chronic kidney failure can achieve end-stage uropathy, that is fatal without artificial filtering (dialysis) or a kidney transplant.


Signs and symptoms of renal failure develop slowly over time if kidney damage progresses slowly. Signs and symptoms of renal failure might include:

Loss of appetite
Fatigue and weakness
Sleep problems
Changes in urine output
Reduced mental sharpness
Muscle twitches and cramps
Swelling of the feet and ankles
Persistent itch
Chest pain, if fluid accumulates around the lining of the heart
Shortness of breath, if fluid accumulates within the lungs
High pressure (hypertension) that is troublesome to manage

Signs and symptoms of usually square measure typically nonspecific, that means they will even be caused by alternative diseases.
Additionally, as a result of your kidneys are highly flexible and able to make amends for lost function, signs and symptoms of kidney failure might not seem until irreversible damage has occurred.

When to see a doctor

Make a meeting along with your doctor if you’ve got any signs or symptoms.

If you’ve got a medical condition that increases your risk of chronic renal failure, your doctor is likely to watch your pressure and kidney function with urine and blood tests throughout regular office visits. ask your doctor whether these types of tests ar right for you.

Factors that will increase your risk of chronic renal failure include:

High pressure
Heart condition
High cholesterol
African-American, Native-American or Asian-American race
family history of uropathy
Age sixty five or older

Chronic renal failure can have an effect on virtually every a part of your body. Potential complications might include:

Fluid retention, that could lead on to swelling in your arms and legs, high pressure, or fluid in your lungs (pulmonary edema)
A fast rise in potassium levels in your blood (hyperkalemia), that might impair your heart’s ability to function and may be severe
Heart and blood vessel illness (cardiovascular disease)
Weak bones and an enhanced risk of bone fractures
Reduced sex drive or impotence
Injury to your central nervous system, which may cause problem concentrating, temperament changes or seizures
reduced immunologic response, that causes you to more liable to infection
Pericarditis, an inflammation of the sac-like membrane that envelops your heart (pericardium)
Maternity complications that carry risks for the mother and also the developing fetus

Irreversible injury to your kidneys (end-stage kidney disease), eventually requiring either dialysis or a kidney transplant for survival

Chronic {kidney failure|renal failure|kidney illness|renal disorder|nephropathy|nephrosis|failure} occurs once a disease or condition impairs kidney function, causing kidney damage to worsen over many months or years.

Diseases and conditions that usually cause chronic renal failure include:

Kind 1 or kind 2 polygenic disorder
High pressure
Nephritis (gloe-mer-u-lo-nuh-FRY-tis), AN inflammation of the kidney’s filtering units (glomeruli)
Polycystic uropathy
Prolonged obstruction of the tract, from conditions like enlarged prostate, kidney stones and a few cancers
Vesicoureteral (ves-ih-koe-yoo-REE-ter-ul) reflux, a condition that causes weewee to make a copy into your kidneys
recurrent kidney infection, additionally called pyelonephritis